CLONIL

Take CLOnil 25 Tablet exactly as prescribed by your doctor. The dose is usually started low and increased gradually to reduce side effects. It may take a few weeks before you notice the full benefits, so it is important not to stop taking it suddenly, even if you feel better. For best results, take the medicine at the same time every day and try not to miss any doses. Common side effects of CLOnil 25 Tablet include dry mouth, constipation, dizziness, drowsiness, blurred vision, increased sweating, and changes in appetite or weight. These are often mild and may improve as your body gets used to the medicine. If you feel very drowsy, avoid driving or operating heavy machinery. If any of these side effects persist or worsen, inform your doctor promptly. CLOnil 25 Tablet should be used with caution in people with heart disease, seizure disorders, glaucoma, or difficulty passing urine. This medicine can increase the risk of suicidal thoughts in some people, especially young adults; therefore, close monitoring at the start of treatment is important. CLOnil 25 Tablet should not be taken together with medicines called monoamine oxidase inhibitors (MAOIs), or within two weeks of stopping them, due to the risk of serious reactions. Alcohol should be avoided as it can worsen drowsiness and other side effects. Pregnant and breastfeeding women should consult their doctors before taking this medicine to make sure it is safe.

Commonly bought for:

SALT CATEGORY: GENERAL

4/7 pharmacies priced

7 pharmacies checked

4 prices found

MedPlusIn stock₹85.28Cheapest— open MedPlus in a new tab
NetmedsIn stock₹236.34+₹151.06— open Netmeds in a new tab
PharmEasyOut of stock₹44.29
PlatinumRxOut of stock₹217.75

No price found yet at 1mg (Tata), Apollo, Truemeds. They may still stock it.

Prices come from pharmacy websites and can change. “Checked” is when we last read that pharmacy's page, not when the price last changed. Confirm on the pharmacy's own page before you order.

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Safety Notice

Never switch or substitute prescribed medications without consulting your treating physician. Equivalent products may differ in excipients, release profiles, or clinical suitability.

TRIFRANIL 25 TABLET

IKON PHARMACHEM PVT LTD

From

₹56.50

medicationDosage & Packaging Details

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Dosage Form

Tablet

Manufacturer

Intas Pharmaceuticals Ltd

Administration

Oral Route

Prescription

prescription

action class: Tricyclic Antidepressants (TCAs)habit forming: Notherapeutic class: NEURO CNS

medical_informationMedicine & Clinical Information

check_circleUses & Indications

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Treatment of Depression
Treatment of Obsessive-compulsive disorder
Treatment of Phobia

lightbulbExpert Advice & Quick Tips

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arrow_rightTake CLOnil 25 Tablet at the same time every day to build a routine and avoid missed doses.
arrow_rightDo not stop the medicine suddenly, even if you feel better; always consult your doctor before making changes.
arrow_rightAvoid driving or operating heavy machines until you know how it affects you, as CLOnil 25 Tablet may cause drowsiness.
arrow_rightLimit or avoid alcohol, as it can increase drowsiness and side effects.
arrow_rightMake sure to attend all follow-up visits with the doctor to monitor your dose and progress.

scienceMechanism of Action (How it works)

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CLOnil 25 Tablet works by increasing the activity of serotonin, a natural chemical messenger in the brain that influences mood, thoughts, and behavior. It blocks the reuptake of serotonin into nerve cells, which helps keep more of it available between brain cells. This action helps reduce obsessive thoughts, lessen compulsive behaviors, ease anxiety from phobias, and improve mood in depression.

infoDirections for Use (How to Use)

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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. CLOnil 25 Tablet should be taken with or after food.

historyMissed Dose Instructions

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If you miss a dose of CLOnil 25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

warningSide Effects

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Nervousness
Myoclonus
Altered libido
Impotence
Fatigue
Increased sweating
Increased appetite
Weight gain
Altered vision
Dryness in mouth
Constipation
Nausea
Indigestion
Decreased appetite
Sleepiness
Tremors
Dizziness

helpFrequently Asked Questions

What is CLOnil 25 Tablet and what does it treat?

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CLOnil 25 Tablet is a tricyclic antidepressant used to treat obsessive-compulsive disorder (OCD), phobic states, and depression (when sedation is helpful). It is often prescribed when obsessive thoughts, intense fears, or depressed mood interfere with daily life.

How long before I notice improvement?

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Some people may notice early improvements in a few weeks, but meaningful benefit for OCD or depression often takes 6–12 weeks, and full effects can take longer. Steady drug levels may take 1–3 weeks after dose changes. Continue taking it for as long as prescribed and do not stop it suddenly.

How should I take it?

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Take it exactly as your doctor prescribes. Treatment usually starts at a low dose and is increased gradually to reduce side effects. Take doses with meals if advised; this will help reduce upset stomach. Take it at the same time each day and ensure to attend all follow-up visits so your doctor can review your dose and response.

Are there any serious risks I should know about?

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Yes. CLOnil 25 Tablet may cause seizures, heart rhythm problems, and can increase suicidal thoughts in young people early in treatment. Do not use it with MAO inhibitors or within 14 days of stopping them due to the risk of life-threatening serotonin syndrome. Get urgent help for new suicidal thoughts, fainting, chest pain, severe heartbeat changes, or signs of serotonin syndrome like high fever, stiff muscles, or confusion.

Editorial & Medical Review

The information on this page has been compiled and reviewed by healthcare professionals and data editors to ensure accuracy. It is for informational and price-comparison purposes only and should not replace professional medical advice.

Written By

MediSaathi Editorial Team

Last Updated

June 21, 2026

Regularly reviewed

Data Sources & Citations

Central Drugs Standard Control Organisation (CDSCO) — Government of IndiaView Source
National Pharmaceutical Pricing Authority (NPPA) — Government of IndiaView Source
Jan Aushadhi Scheme — Pradhan Mantri Bhartiya Janaushadhi Pariyojana — Government of IndiaView Source

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CLONIL

7 pharmacies checked

vaccinesMost Viewed Alternatives

Doctor Consultation Required

medical_informationMedicine & Clinical Information

helpFrequently Asked Questions

Editorial & Medical Review

Data Sources & Citations