Can Empagreat-M 500 Tablet cause low blood sugar?

Empagreat-M 500 Tablet alone has a low risk of hypoglycaemia, but the risk increases when used with insulin or sulfonylureas. A dose reduction of insulin or sulfonylurea may be needed to lower the risk of low blood sugar.

EMPAGREAT M 500 TABLET

a combination of empagliflozin and metformin as active substances

a combination of empagliflozin and metformin as active substancesSalt

Empagreat M Tablet is an anti-diabetic medication. It contains a combination of empagliflozin and metformin as active substances. Empagreat M Tablet is used for the management of type 2 diabetes in adults along with diet and exercise. Type 2 diabetes is a condition where your pancreas does not make enough insulin to effectively control the blood sugar level and your body is unable to use its own insulin effectively. This medicine works by lowering the blood sugar level. Take Empagreat M Tablet in the exact dose and duration as prescribed by your doctor. Before starting this medicine, inform your doctor if you are pregnant/breastfeeding and about your complete medical history. It is important to make certain lifestyle changes like having a balanced diet and regular exercise along with this medicine to help to manage blood sugar levels better.

Commonly bought for:

SALT CATEGORY: GENERAL

5/7 pharmacies priced

7 pharmacies checked

5 prices found

No price found yet at 1mg (Tata), Truemeds. They may still stock it.

Prices come from pharmacy websites and can change. “Checked” is when we last read that pharmacy's page, not when the price last changed. Confirm on the pharmacy's own page before you order.

medicationDosage & Packaging Details

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Dosage Form

Tablet

Manufacturer

MANKIND PHARMACEUTICALS LTD

Administration

Oral Route

Prescription

prescription

habit forming: Notherapeutic class: ANTI DIABETIC

medical_informationMedicine & Clinical Information

check_circleUses & Indications

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Treatment of Type 2 diabetes mellitus

lightbulbExpert Advice & Quick Tips

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arrow_rightYou have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
arrow_rightIt also reduces the risk of heart attack, heart failure or other cardiovascular events.
arrow_rightYou should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) along with Empagreat-M 500 Tablet.
arrow_rightTake it with food to lower your chance of having an upset stomach.
arrow_rightPractice good genital hygiene to prevent yeast or urinary tract infections
arrow_rightIt may cause your body to lose too much fluid (dehydration) or you to urinate more often. Drink plenty of water and stay hydrated.
arrow_rightIt can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Monitor your blood sugar level regularly.
arrow_rightAlways carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.

scienceMechanism of Action (How it works)

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Empagreat-M 500 Tablet is a combination of two antidiabetic medicines: Empagliflozin and Metformin. Empagliflozin works by removing excess glucose from your body through urine. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Together, they lower blood glucose more effectively.

infoDirections for Use (How to Use)

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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Empagreat-M 500 Tablet may be taken with or without food.

historyMissed Dose Instructions

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If you miss a dose of Empagreat-M 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

warningSide Effects

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Nausea
Headache
Dizziness
Fatigue
Diarrhea
Abdominal pain
Vomiting
Constipation
Rash

helpFrequently Asked Questions

What is Empagreat-M 500 Tablet used for?

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Empagreat-M 500 Tablet is a combination medicine used to treat type 2 diabetes. Along with a proper diet and regular exercise, it helps improve blood sugar control in adults. It works by enhancing the body’s ability to use insulin effectively, thereby lowering blood sugar levels.

Who should not take Empagreat-M 500 Tablet?

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People should not take Empagreat-M 500 Tablet if they have severe kidney failure (eGFR below 30 mL/min/1.73 m²), during diabetic pre-coma, with active ketoacidosis or lactic acidosis, in severe liver disease, in acute conditions that reduce oxygen to tissues (such as decompensated heart failure or shock), or with a known allergy to either ingredient present in it.

What serious side effects of Empagreat-M 500 Tablet need urgent care?

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Seek emergency help if you experience serious side effects of Empagreat-M 500 Tablet, such as signs of lactic acidosis (trouble breathing, stomach pain, severe weakness, confusion, vomiting), or diabetic ketoacidosis (nausea, vomiting, belly pain, deep breathing, unusual fatigue, fruity breath).

Can Empagreat-M 500 Tablet affect the kidneys or fluid balance?

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Yes, empagliflozin medicine present in Empagreat-M 500 Tablet increases urination and can lead to dehydration and low blood pressure, especially in older adults or with diuretics. Kidney function should be checked before starting and periodically during treatment, and more often if kidney function is at risk.

Are there infection risks to watch for during Empagreat-M 500 Tablet?

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Yes, urinary tract infections (including kidney infection and sepsis) and genital infections can occur during Empagreat-M 500 Tablet treatment. Very rare cases of a serious genital area infection called Fournier’s gangrene need urgent surgery and antibiotics. Seek care for pain, swelling, redness in the genital/perineal area with fever or feeling unwell.

Editorial & Medical Review

The information on this page has been compiled and reviewed by healthcare professionals and data editors to ensure accuracy. It is for informational and price-comparison purposes only and should not replace professional medical advice.

Written By

MediSaathi Editorial Team

Last Updated

June 21, 2026

Regularly reviewed

Data Sources & Citations

Central Drugs Standard Control Organisation (CDSCO) — Government of IndiaView Source
National Pharmaceutical Pricing Authority (NPPA) — Government of IndiaView Source
Jan Aushadhi Scheme — Pradhan Mantri Bhartiya Janaushadhi Pariyojana — Government of IndiaView Source

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Is EMPAGREAT M 500 TABLET available at a cheaper price in India?

Price Summary for EMPAGREAT M 500 TABLET

EMPAGREAT M 500 TABLET

7 pharmacies checked

medical_informationMedicine & Clinical Information

helpFrequently Asked Questions

Editorial & Medical Review

Data Sources & Citations