PROFINE SR 300 TABLET

Progesterone (Natural Micronized) (300mg)

Progesterone (Natural Micronized) (300mg)Salt

Profine SR 300 Tablet is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused by hormonal imbalance. Profine SR 300 Tablet is also prescribed, along with estrogen, as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.The most common side effects include headache, breast pain, irregular vaginal bleeding or spotting, stomach or abdominal cramps, bloating, nausea and vomiting, hair loss, edema, and vaginal yeast infection. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods; consult with your doctor if it happens frequently.Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking, as some may affect, or be affected by, this medicine. In general, it is advisable to avoid alcohol and smoking.

Commonly bought for:

SALT CATEGORY: GENERAL

3/7 pharmacies priced

7 pharmacies checked

3 prices found

ApolloIn stock₹50.00Cheapest— open Apollo in a new tab
NetmedsIn stock₹542.34+₹492.34— open Netmeds in a new tab
PlatinumRxOut of stock₹499.69

No price found yet at PharmEasy, 1mg (Tata), Truemeds, MedPlus. They may still stock it.

Prices come from pharmacy websites and can change. “Checked” is when we last read that pharmacy's page, not when the price last changed. Confirm on the pharmacy's own page before you order.

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Never switch or substitute prescribed medications without consulting your treating physician. Equivalent products may differ in excipients, release profiles, or clinical suitability.

GESTOSERV 300 SR TABLET

Leeford Healthcare Ltd (Generics)

From

₹210.00

medicationDosage & Packaging Details

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Dosage Form

Tablet SR

Manufacturer

Profine

Administration

Oral Route

Prescription

prescription

action class: Natural Progesteronehabit forming: Notherapeutic class: GYNAECOLOGICAL

medical_informationMedicine & Clinical Information

check_circleUses & Indications

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Treatment of Female infertility
Hormone replacement therapy

lightbulbExpert Advice & Quick Tips

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arrow_rightProfine SR 300 Tablet may also be used in the treatment of problems related to the menstrual period, such as amenorrhea (absence of periods).
arrow_rightIt also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.
arrow_rightIt should be taken with food.
arrow_rightIt may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.

scienceMechanism of Action (How it works)

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Profine SR 300 Tablet is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.

infoDirections for Use (How to Use)

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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Profine SR 300 Tablet should be taken with or after food.

historyMissed Dose Instructions

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If you miss a dose of Profine SR 300 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

warningSide Effects

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Nausea
Dizziness
Fatigue
Headache
Breast tenderness
Bloating
Mood changes
Vaginal discharge
Abdominal pain

helpFrequently Asked Questions

What is Profine SR 300 Tablet?

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Profine SR 300 Tablet is a type of progesterone hormone which is extracted from plants, but its properties match those of human progesterone. This medicine undergoes a process called micronization, where the size of the natural progesterone is reduced. The small size of the progesterone particles enhances its dissolution and absorption. This provides better availability of Profine SR 300 Tablet in the body and decreases its side effects.

What is Profine SR 300 Tablet used to treat?

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Profine SR 300 Tablet is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in women who have had their menses before). It is used to support pregnancy, prevent premature labor, and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding, like in dysfunctional uterine bleeding.

Can you take Profine SR 300 Tablet every day?

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Yes, Profine SR 300 Tablet can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor, depending on your health condition.

Does Profine SR 300 Tablet cause weight gain?

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Yes, taking Profine SR 300 Tablet may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Profine SR 300 Tablet is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

How is progesterone beneficial for fertility and pregnancy?

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Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. Profine SR 300 Tablet (natural micronized form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent abortions in some cases. It is also used to prevent premature labor.

Editorial & Medical Review

The information on this page has been compiled and reviewed by healthcare professionals and data editors to ensure accuracy. It is for informational and price-comparison purposes only and should not replace professional medical advice.

Written By

MediSaathi Editorial Team

Last Updated

June 21, 2026

Regularly reviewed

Data Sources & Citations

Central Drugs Standard Control Organisation (CDSCO) — Government of IndiaView Source
National Pharmaceutical Pricing Authority (NPPA) — Government of IndiaView Source
Jan Aushadhi Scheme — Pradhan Mantri Bhartiya Janaushadhi Pariyojana — Government of IndiaView Source

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Price Summary for PROFINE SR 300 TABLET

PROFINE SR 300 TABLET

7 pharmacies checked

vaccinesMost Viewed Alternatives

Doctor Consultation Required

medical_informationMedicine & Clinical Information

helpFrequently Asked Questions

Editorial & Medical Review

Data Sources & Citations